Other
p-Chlorobenzotrichloride
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
P-Chlorobenzotrichloride is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.
p-Chlorobenzotrichloride (4-chlorobenzotrichloride) is a highly chlorinated aromatic compound used primarily as a chemical intermediate in industrial synthesis, not in cosmetic formulations. The presence of three chlorine atoms on the benzylic carbon creates extreme lipophilicity and toxicity concerns. Under EU Regulation 1223/2009, substances classified as CMR 1A or 1B are prohibited for cosmetic use and listed in Annex II regardless of intended function. The compound demonstrates carcinogenic and mutagenic activity in toxicological studies, presenting unacceptable risk for any cosmetic application. Any presence as a manufacturing impurity is subject to strict control and is typically not detectable in high-purity cosmetic-grade raw materials.
Known concerns
- CMR 1B classification - presumed carcinogen, mutagen, reproductive toxicant
- EU Annex II ban for cosmetic use
- Extremely high toxicity concern
- Industrial chemical only, not appropriate for cosmetic formulation
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related others
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.