P-CRESYL 3-OXO-3-PHENYLPROPIONATE

Other

60

Moderate

CAS Number: 67801-43-8

About P-CRESYL 3-OXO-3-PHENYLPROPIONATE

P-Cresyl 3-Oxo-3-Phenylpropionate is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Detailed Analysis

p-Cresyl 3-oxo-3-phenylpropionate (also called p-tolyl 3-oxo-3-phenylpropionate) is an ester of p-cresol with phenylpyruvic acid. The compound is listed in the EU CosIng database and used as a fragrance ingredient in cosmetics. The cresol component introduces regulatory attention since p-cresol and its derivatives are subject to assessment under EU Regulation 1223/2009 for phenols and aromatic hydroxy compounds. RIFM and IFRA have assessed this ester and provided use level guidelines to manage any cresol-related toxicity concerns while allowing safe use in fragrance applications.

Skin Benefits

  • Sweet, herbaceous-spicy fragrance with good substantivity
  • Used as a floralizer and fixative in perfume compositions

Known Concerns

  • Cresol component subject to EU regulatory scrutiny for phenolics
  • Fragrance allergen declaration thresholds apply
  • IFRA guidelines control use levels in various product categories
  • Potential for hydrolysis releasing cresol in skin contact applications

Safety Score

60

Moderate

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.