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P-VINYLPHENOL

CAS 2628-17-3
38

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

P-Vinylphenol is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

p-Vinylphenol (4-vinylphenol) is a phenolic compound containing an ethenyl group that imparts reactivity and potential for polymerization. The vinyl group can undergo free-radical polymerization, raising concerns about stability in cosmetic formulations and potential skin sensitization from reactive intermediates. EU cosmetic regulations treat compounds with unsaturated reactive groups with caution, as they may form polymers or degrade to reactive species that penetrate skin and cause sensitization. The phenolic OH also contributes to skin irritation potential. While not explicitly banned, such reactive monomers are typically restricted to low concentrations in stable formulations with adequate safety data.

Known concerns

  • Skin sensitization from reactive vinyl group
  • Potential for polymerization creating unstable formulations
  • Skin irritation from phenolic structure
  • Limited comprehensive safety data for cosmetic use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.