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Skin Conditioning

PALMITOYL HEXAPEPTIDE-12

CAS 171263-26-6
78

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Palmitoyl hexapeptide-12 — a lipidated signal peptide marketed for firmness and elasticity. Well tolerated; clinical evidence is modest compared with the marketing.

Function

SKIN CONDITIONING

Skin benefits

  • Signal peptide for skin firmness
  • Low-irritation profile
  • Supports collagen feel

Known concerns

  • Marketing claims often exceed clinical evidence
  • High cost vs benefit varies

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

PC

PubChem

U.S. NIH compound data, GHS hazard codes and toxicity literature.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.