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PALMITOYL TRIPEPTIDE-1 ACETATE

82

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A fatty acid conjugated tripeptide combining the collagen-stimulating benefits of Tripeptide-1 with enhanced skin delivery via palmitoyl modification.

Palmitoyl Tripeptide-1 is a GHK-family tripeptide conjugated to palmitic acid to enhance skin penetration and cellular uptake. It is listed in EU CosIng without restrictions and is one of the most widely used anti-aging peptides globally. The palmitoyl group acts as a penetration enhancer and also provides some emollient benefits. Clinical evidence supports its efficacy in reducing wrinkle depth and improving skin firmness. Safe for cosmetic use at standard concentrations.

Skin benefits

  • Enhanced skin penetration via palmitoyl carrier
  • Stimulates collagen I and III
  • Firms and plumps skin
  • Reduces wrinkle depth

Known concerns

  • Very rare contact allergy reported in sensitised individuals

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.