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PANTOTHENAMIDE MEA

80

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Pantothenamide Mea is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Pantothenamide MEA is an amide derivative of pantothenic acid (vitamin B5) where the carboxylic acid is amidated with monoethanolamine (MEA), creating a more oxidation-stable form. It is not subject to EU Annex restrictions and functions as a skin-conditioning active with humectant and barrier-support properties. Unlike panthenol (the common vitamin B5 cosmetic ingredient), the amide form avoids oxidation-related color and odor issues in formulations while providing comparable skin benefits. The MEA component is regulated under III/62 but at this structural modification the nitrosamine risk is considered negligible.

Skin benefits

  • Humectant and skin-moisturizing properties
  • Supports skin barrier repair and regeneration
  • Anti-inflammatory and soothing effects (vitamin B5 class)

Known concerns

  • Theoretical nitrosamine concern from MEA component — negligible given amide bond
  • Limited specific toxicological data compared to panthenol

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.