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PEG-220

CAS 25322-68-3
86

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A high molecular weight polyethylene glycol (~220 EO units) acting as a thickener, binder, and film-former in cosmetic products, with negligible skin penetration due to its large polymer size.

PEG-220 is a polyethylene glycol polymer with an average of 220 moles of ethylene oxide per molecule, giving it a molecular weight in the range where skin penetration is essentially negligible. It functions primarily as a viscosity-controlling agent, binder, and humectant in cosmetic formulations. EU Regulation (EC) 1223/2009 does not restrict high molecular weight PEG polymers. Purity considerations (residual ethylene oxide, 1,4-dioxane, and catalyst metals) are the primary quality concerns, and compliance with SCCS Notes of Guidance ensures safety at typical use concentrations.

Skin benefits

  • Thickens and stabilizes cosmetic formulations
  • Provides humectant film on skin surface
  • Inert polymer with broad formulation compatibility

Known concerns

  • Residual 1,4-dioxane and ethylene oxide must be controlled per SCCS standards
  • May contain trace heavy metal catalysts from polymerization

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.