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Skin Conditioning

PENTAPEPTIDE-57

65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A synthetic five-amino-acid peptide used as a skin-conditioning active. Low-risk by peptide class; specific evidence is thin.

Pentapeptide-57 is a defined-sequence five-amino-acid synthetic peptide used in skin-conditioning formulations. Pentapeptides have a clean class safety record in cosmetics — low irritation, minimal sensitization, rapid breakdown into amino acids by skin proteases. No specific CIR or SCCS opinion exists for this peptide. Independent peer-reviewed efficacy data is essentially absent; most claims rely on supplier in vitro and small-panel work.

Function

SKIN CONDITIONING

Skin benefits

  • Skin conditioning
  • Low irritation
  • Defined synthetic sequence

Known concerns

  • Limited independent data
  • No regulatory review
  • Supplier-driven claims

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.