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Skin Conditioning

PENTASODIUM TETRACARBOXYMETHYL ACETYLHYDROXYPROLYL DIPEPTIDE-12

78

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A synthetic brightening dipeptide (PTPD-12) that activates autophagy and degrades melanosomes. Clinical trial reports good tolerance and efficacy.

Function

SKIN CONDITIONING

Skin benefits

  • Synthetic dipeptide for hyperpigmentation
  • Enhances autophagy in keratinocytes
  • Clinical trial supports brightening efficacy

Known concerns

  • Synthetic peptide with limited long-term data
  • Possible mild irritation
  • Not formally CIR-reviewed

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.