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Pharmaceutical (non-cosmetic)

pethidine

CAS 57-42-1
3

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Pethidine (meperidine) — a controlled opioid analgesic and prescription drug. EU Annex II prohibits it in cosmetics; if seen on a cosmetic label, it indicates serious mislabeling or adulteration.

Skin benefits

  • Primarily a processing aid

Known concerns

  • Controlled opioid — prohibited in cosmetics
  • Respiratory depression, dependence
  • Neurotoxic norpethidine metabolite

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.