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Skin Conditioning

PIPER METHYSTICUM LEAF/ROOT/STEM EXTRACT

CAS 84696-40-2 Updated
48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Kava (Piper methysticum) extract — CIR judged insufficient data to confirm cosmetic safety; oral use is linked to liver toxicity and topical use can cause kawa dermopathy. Use with caution.

Function

SKIN CONDITIONING

Skin benefits

  • Anti-inflammatory kavalactones
  • Mild antimicrobial activity

Known concerns

  • CIR insufficient-data conclusion for cosmetics
  • Hepatotoxicity reports (oral) extrapolation uncertain
  • Kawa dermopathy on chronic topical use
  • Restricted as medicinal in several jurisdictions

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.