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Skin Conditioning

PNA-5 CARBOXYETHYL FLUORENE

55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A synthetic peptide nucleic acid (PNA) polymer carrying 12 nucleobases on a fluorene backbone, marketed for advanced skin biology effects. Almost no public safety data exists for this novel class, which is why it sits in cautious orange.

Function

NOT REPORTED

Skin benefits

  • Marketed as advanced skin-conditioning agent
  • Engineered to interact with biological molecules on skin
  • Synthetic backbone — non-allergenic protein source

Known concerns

  • Novel synthetic polymer — very limited public toxicology
  • Designed to bind nucleic acids — long-term effects on skin biology not characterized
  • No CIR or SCCS assessment available
  • Class includes nucleobases that are reactive small molecules

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.