Pharmaceutical (prohibited in cosmetics)
Poldine metilsulfate (INN)
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
Poldine metilsulfate is a pharmaceutical anticholinergic drug, prohibited as a cosmetic ingredient under EU Annex II; it has no cosmetic use and exhibits systemic side effects when absorbed.
Skin benefits
- Anticholinergic pharmaceutical used historically to treat peptic ulcers and hyperhidrosis
- Has medicinal applications under prescription
- No legitimate cosmetic application
Known concerns
- Pharmaceutical anticholinergic, not a cosmetic ingredient
- Prohibited in cosmetics under EU Annex II as a medicinal substance
- Systemic anticholinergic effects: dry mouth, blurred vision, urinary retention, tachycardia
- Contraindicated in glaucoma and several other conditions
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related pharmaceutical (prohibited in cosmetics)s
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.