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POLYGLYCERIN-4

CAS 56491-53-3
85

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A moisture-attracting polymer made from glycerin units — acts as a humectant and helps stabilise formulations. Very gentle and well-tolerated.

Polyglycerin-4 (CAS 56491-53-3) is a tetramer of glycerol produced by condensation polymerisation. It functions as a humectant with excellent water-binding capacity, and as a co-emulsifier in cosmetic formulations. Its hygroscopic nature makes it effective at maintaining skin hydration. No GHS hazards or EU restrictions. CIR has assessed polyglycerol compounds as safe for cosmetic use.

Skin benefits

  • Strong humectant properties
  • Helps stabilise emulsions
  • Non-irritating moisturiser
  • Glycerin-derived, gentle on skin

Known concerns

  • No significant concerns identified at typical cosmetic concentrations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.