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Banned Substance

procaine

CAS 59-46-1 Updated
6

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A classic ester-type local anaesthetic (Novocaine). Procaine and its salts are listed in EU Annex II as prohibited cosmetic ingredients — pharmacologically active and a known contact allergen.

Skin benefits

  • Not applicable — not permitted in cosmetics

Known concerns

  • EU Annex II prohibited
  • Ester anaesthetic allergen
  • Cross-reacts with other PABA-derived anaesthetics
  • Systemic activity

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.