Skip to content

Other

PROPAFENONE

CAS 54063-53-5
22

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Propafenone is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Propafenone is a Class IC antiarrhythmic agent that acts on cardiac sodium channels. It has no cosmetic function and is not listed in EU cosmetic regulation Annexes. As a systemic pharmaceutical with significant side effects (proarrhythmic effects, negative inotropic activity), it has no place in topical cosmetic formulations. Any presence in a cosmetic ingredient list would represent contamination, not intentional addition.

Known concerns

  • Pharmaceutical agent — no cosmetic function
  • Significant cardiac side effects
  • Not assessed for topical safety

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related others

22
(4-Ethoxyphenyl)(3-(4-fluoro-3-phenoxyphenyl)propyl)dimethylsilane
Other
 22
1,3-Benzenediamine, 4-methyl-, hydrochloride (1:2)
Other
 22
1,4-BUTANEDIOL DIMETHACRYLATE
Other
 22
1-NITROPROPANE
Other
 22
3-Chloro-4-(3-fluorobenzyloxy)aniline
Other
 22
4-T-BUTYLBENZOIC ACID
Other
 22
4-tert-Butylbenzoic acid
Other
 22
BUTYLPHTHALIMIDE
Other

Check your shelf

Find PROPAFENONE in your products.

Scan any cosmetic product with LuxSense to see if it contains PROPAFENONE and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.