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PROPAFENONE

CAS 54063-53-5
22

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Propafenone is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Propafenone is a Class IC antiarrhythmic agent that acts on cardiac sodium channels. It has no cosmetic function and is not listed in EU cosmetic regulation Annexes. As a systemic pharmaceutical with significant side effects (proarrhythmic effects, negative inotropic activity), it has no place in topical cosmetic formulations. Any presence in a cosmetic ingredient list would represent contamination, not intentional addition.

Known concerns

  • Pharmaceutical agent — no cosmetic function
  • Significant cardiac side effects
  • Not assessed for topical safety

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.