R-2,3-Epoxy-1-propanol

Other

5

Avoid

CAS Number: 57044-25-4

About R-2,3-Epoxy-1-propanol

R-2,3-Epoxy-1-propanol is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Detailed Analysis

Glycidol (R-2,3-epoxy-1-propanol) is classified H350 (may cause cancer) and appears on EU Annex III restricted substances list due to its carcinogenic and genotoxic profile. As a reactive epoxide, it can form covalent adducts with skin proteins and DNA. Its use in cosmetic products is either prohibited or severely restricted under EU cosmetics regulation, and it has no published benefit for topical application.

Known Concerns

  • Probable carcinogen (H350)
  • Genotoxic epoxide reactivity
  • EU Annex III restricted
  • Severe acute toxicity potential

Safety Score

5

Avoid

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.