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R-2,3-Epoxy-1-propanol

CAS 57044-25-4
5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

R-2,3-Epoxy-1-propanol is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Glycidol (R-2,3-epoxy-1-propanol) is classified H350 (may cause cancer) and appears on EU Annex III restricted substances list due to its carcinogenic and genotoxic profile. As a reactive epoxide, it can form covalent adducts with skin proteins and DNA. Its use in cosmetic products is either prohibited or severely restricted under EU cosmetics regulation, and it has no published benefit for topical application.

Known concerns

  • Probable carcinogen (H350)
  • Genotoxic epoxide reactivity
  • EU Annex III restricted
  • Severe acute toxicity potential

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.