Conditioning Agent
R-(SH-POLYPEPTIDE-119 DECAPEPTIDE-40)
Safety score · 0–100
Good
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A lab-made peptide used to condition skin and support a smoother, more refined feel.
r-(sh-Polypeptide-119 Decapeptide-40) is a single chain recombinant peptide, produced by fermentation in E. coli. The starting gene is synthesized by the fusion of the genes encoding for sh-Polypeptide-119 and Decapeptide-40. The fusion peptide contains 122 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids. As a synthetic or recombinant peptide, it is typically used at very low levels and is generally considered low risk, though human data are often limited compared with older staple ingredients.
Function
Skin benefits
- Skin-conditioning support
Known concerns
- Limited long-term data for some newer cosmetic peptides
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related conditioning agents
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.