Conditioning Agent
RH-POLYPEPTIDE-92
Safety score · 0–100
Good
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A recombinant human growth factor peptide produced in HEK 293 mammalian cells, subject to EU Annex II/416 restriction due to eukaryotic production.
A recombinant human peptide corresponding to Growth Differentiation Factor 11, produced in HEK 293 mammalian cell culture rather than bacteria. Subject to EU Cosmetics Regulation Annex II/416 due to recombinant protein status. Mammalian cell production introduces additional considerations for endotoxin and host cell protein residues. No GHS hazards reported. Safety profile is dependent on rigorous purification.
Function
Skin benefits
- Skin conditioning
- Supports skin regeneration
Known concerns
- Subject to EU Annex II/416 special assessment
- Mammalian cell production requires careful impurity profiling
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related conditioning agents
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.