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Antimicrobial

RHEIN

CAS 478-43-3 Updated
40

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

An anthraquinone derived from rhubarb and senna with antimicrobial and antioxidant properties. Hydroxyanthraquinones carry genotoxicity and photosensitization concerns, so cosmetic use needs careful justification.

Function

ANTIMICROBIAL

Skin benefits

  • Antimicrobial activity in vitro
  • Antioxidant potential
  • Anti-inflammatory in some studies

Known concerns

  • Genotoxicity flag for hydroxyanthraquinones
  • Skin/mucosal irritation potential
  • Photosensitization risk
  • Pigment/staining issues

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.