Skip to content

Other

RHODODENDROL

CAS 69617-84-1
22

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Rhododendrol is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Rhododendrol (also called rhododendron extract or 4-butylresorcinol derivative) is a phenolic compound that inhibits tyrosinase activity for skin-lightening purposes. It has been banned or severely restricted in cosmetics across multiple major markets including the EU, Japan, and South Korea following safety concerns and reported cases of exogenous ochronosis and skin depigmentation beyond intended use areas. The EU's prohibition reflects concerns that tyrosinase inhibitors in this structural class can cause irreversible pigmentation changes. This compound represents a regulatory boundary case for cosmetic skin-lightening ingredients.

Skin benefits

  • Tyrosinase inhibition for skin-lightening cosmetic applications (where permitted)
  • Alternative to hydroquinone in some markets

Known concerns

  • Banned or restricted in cosmetics across EU, Japan, and South Korea
  • Cases of exogenous ochronosis and unwanted depigmentation reported
  • Irreversible pigmentation changes in post-market surveillance
  • Tyrosinase inhibitor class carries elevated regulatory scrutiny
  • Reported cross-reactivity with other skin-lightening agents

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

22
(4-Ethoxyphenyl)(3-(4-fluoro-3-phenoxyphenyl)propyl)dimethylsilane
Other
 22
1,3-Benzenediamine, 4-methyl-, hydrochloride (1:2)
Other
 22
1,4-BUTANEDIOL DIMETHACRYLATE
Other
 22
1-NITROPROPANE
Other
 22
3 and 4-(4-Hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde
Other
 22
3-Chloro-4-(3-fluorobenzyloxy)aniline
Other
 22
4,4'-Carbonimidoylbis[N,N-dimethylaniline] and its salts
Other
 22
4-T-BUTYLBENZOIC ACID
Other

Check your shelf

Find RHODODENDROL in your products.

Scan any cosmetic product with LuxSense to see if it contains RHODODENDROL and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.