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Conditioning Agent

SH-OLIGOPEPTIDE-78 DI-(S-SILKWORM HEXAPEPTIDE-1) TRI-(PENTAPEPTIDE-120)

86

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A complex synthetic peptide containing multiple repeating sequences from human, silkworm, and synthetic peptide sources for hair conditioning.

This multi-domain synthetic peptide combines sh-Oligopeptide-78 with two copies of silkworm hexapeptide and three copies of pentapeptide-120, for a total of 40 amino acids. The silkworm-derived component introduces a non-human protein source that could theoretically cause allergic responses in individuals sensitized to silk. The EU treats such multi-source peptides under general cosmetic safety rules, with no specific regulatory restrictions identified.

Function

HAIR CONDITIONING

Skin benefits

  • Hair conditioning

Known concerns

  • Silk/worm-derived allergenicity possible for insect-allergic individuals

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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Check your shelf

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.