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Skin Conditioning

SH-PENTAPEPTIDE-5

78

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A synthetic five-amino-acid peptide modeled on a portion of the natural neuropeptide Leu-Enkephalin, used in soothing skin care. Short synthetic peptide with limited topical safety data.

Function

SKIN CONDITIONING

Skin benefits

  • Skin conditioning
  • Soothing and calming claims based on enkephalin motif
  • Short synthetic peptide with low irritancy potential

Known concerns

  • No CIR or SCCS review
  • Bioactivity claims rest on mechanism, not topical evidence
  • Neuropeptide-mimetic ingredients raise theoretical bioactivity questions

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.