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Skin Conditioning

SH-POLYPEPTIDE-45

78

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A lab-made copy of human GM-CSF — a potent immune signal protein. Used in skincare at minute doses; held to a cautious tier because GM-CSF activity is biologically powerful.

Function

SKIN CONDITIONING

Skin benefits

  • Recombinant GM-CSF analog supports skin conditioning
  • High-purity E. coli expression
  • Used at very low doses

Known concerns

  • GM-CSF is a potent immune signaling factor — caution warranted
  • Limited public cosmetic safety data
  • Theoretical immunogenicity

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.