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Humectant

SODIUM HISTIDYL HYALURONATE CROSSPOLYMER-3

90

Safety score · 0–100

Excellent

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A crosslinked hyaluronic acid coupled with histidine — a moisture magnet that resists enzymatic breakdown for longer-lasting hydration than standard HA. Excellent safety profile.

Function

HUMECTANTSKIN CONDITIONING

Skin benefits

  • Strong, longer-lasting skin hydration vs. standard hyaluronic acid
  • Resists enzymatic breakdown by skin hyaluronidase
  • Histidine residue adds mild buffering and antioxidant effect
  • Excellent skin tolerance

Known concerns

  • Higher cost than standard HA
  • Crosslinking chemistry must use food/cosmetic-grade crosslinkers

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related humectants

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.