Humectant
SODIUM HISTIDYL HYALURONATE CROSSPOLYMER-3
Safety score · 0–100
Excellent
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A crosslinked hyaluronic acid coupled with histidine — a moisture magnet that resists enzymatic breakdown for longer-lasting hydration than standard HA. Excellent safety profile.
Function
Skin benefits
- Strong, longer-lasting skin hydration vs. standard hyaluronic acid
- Resists enzymatic breakdown by skin hyaluronidase
- Histidine residue adds mild buffering and antioxidant effect
- Excellent skin tolerance
Known concerns
- Higher cost than standard HA
- Crosslinking chemistry must use food/cosmetic-grade crosslinkers
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related humectants
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.