Skip to content

SOPHORA FLAVESCENS ROOT POWDER

CAS -
50

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Ku Shen root powder, a traditional Chinese herb used in skincare for its anti-inflammatory, antifungal, and skin-purifying benefits.

Sophora flavescens contains quinolizidine alkaloids (matrine, oxymatrine, sophocarpine) that have documented pharmacological activity but also toxicity at high doses. High oral doses of matrine/oxymatrine have been associated with gastrointestinal and neurological effects in Chinese medicine literature. Topically, the allergenicity risk is moderate, and EU Annex III sets limits for certain alkaloid-containing plants. The ingredient is not broadly banned but requires careful handling and low use concentrations.

Skin benefits

  • Matrine has anti-inflammatory activity against acne-related bacteria
  • Traditional use for eczema and pruritus

Known concerns

  • Matrine and oxymatrine are potential sensitizers; documented contact dermatitis cases
  • EU import and use levels should be monitored for future regulation
  • Oral toxicity reported at high doses; topical limit advisable

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Check your shelf

Find SOPHORA FLAVESCENS ROOT POWDER in your products.

Scan any cosmetic product with LuxSense to see if it contains SOPHORA FLAVESCENS ROOT POWDER and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.