Antimicrobial
SR-MOUSE POLYPEPTIDE-5
Safety score · 0–100
Good
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A recombinant mouse immunoglobulin derivative with antimicrobial properties, produced in E. coli for skin conditioning.
SR-Mouse Polypeptide-5 is derived from mouse Immunoglobulin Heavy Chain Variable Region and produced in E. coli. The use of mouse-derived sequence in a bacterial expression system raises concerns about potential immunogenic responses in humans, particularly with repeated topical use. The SCCS has not issued specific guidance on this ingredient, and it is not listed in either Annex II (banned) or Annex III (restricted) of the EU cosmetics regulation.
Function
Skin benefits
- Antimicrobial activity
- Skin conditioning
Known concerns
- Mouse-derived sequence may trigger immunogenic responses
- Endotoxin risk from E. coli production
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related antimicrobials
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.