Other
SR-RABBIT POLYPEPTIDE-4
Safety score · 0–100
Good
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A recombinant protein based on rabbit immunoglobulin sequence, produced in human embryonic kidney (HEK) cells for skin conditioning.
SR-Rabbit Polypeptide-4 is a unique recombinant protein derived from rabbit Ig kappa-b4 chain C region, produced in Human Embryonic Kidney (HEK) cells rather than microbial systems. While the HEK expression system produces more human-like glycosylation, the use of an animal-derived sequence raises theoretical immunogenicity concerns. It is not specifically restricted under EU cosmetics law, but its novel profile warrants monitoring.
Function
Skin benefits
- Skin conditioning
Known concerns
- Theoretical immunogenicity due to rabbit sequence in human cell expression system
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related others
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.