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TDI OXIDIZED MICROCRYSTALLINE WAX

58

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A petroleum-derived microcrystalline wax chemically modified with toluene diisocyanate to change its physical properties — the isocyanate group introduces sensitization and respiratory concerns that make it controversial for skin products.

TDI Oxidized Microcrystalline Wax is the reaction product of oxidized microcrystalline petroleum wax with toluene diisocyanate (2,4-TDI and/or 2,6-TDI isomers). The reaction introduces urethane linkages into the wax matrix, increasing hardness and adhesion. Toluene diisocyanate is a known respiratory sensitizer and is classified under GHS H332 (harmful if inhaled) and H317 (may cause allergic skin reaction). Its use in leave-on skin products is questionable; it is more commonly found in industrial coatings and adhesives.

Known concerns

  • Respiratory sensitization potential from TDI
  • Skin sensitization (H317) from isocyanate groups
  • Not recommended for leave-on skin formulations
  • Industrial chemical repurposed for cosmetics

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.