Other
TETRAPEPTIDE-105 BIS-CYCLOHEXYLPROPYL HISTIDINAMIDE
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A larger histidine-rich peptide analogue of the tripeptide variant, used for similar anti-aging and conditioning benefits.
Tetrapeptide-105 bis-cyclohexylpropyl histidinamide is a four-amino-acid peptide with the same cyclohexylpropyl histidinamide capping as the tripeptide analogue (tripeptide-107). The additional amino acid in the peptide chain may slightly modify the activity and receptor interaction profile. Both cyclohexyl groups and histidinamide residues are well-tolerated structural elements in topical formulations. The tetrapeptide version offers a different potency and binding profile compared to the tripeptide, allowing formulation flexibility. Not restricted under EU cosmetics law.
Skin benefits
- Skin conditioning
- Anti-aging
- Barrier support from histidine-based NMF components
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related others
Check your shelf
Find TETRAPEPTIDE-105 BIS-CYCLOHEXYLPROPYL HISTIDINAMIDE in your products.
Scan any cosmetic product with LuxSense to see if it contains TETRAPEPTIDE-105 BIS-CYCLOHEXYLPROPYL HISTIDINAMIDE and get a full ingredient breakdown with safety scores.
This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.