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Skin Conditioning

THIAMINE/YEAST POLYPEPTIDE

CAS -
65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A yeast-derived peptide complex carrying thiamine (vitamin B1) — used to condition skin. Generally well tolerated, though clinical evidence is limited.

Thiamine/Yeast Polypeptide is a hybrid ingredient made by fermenting yeast in the presence of thiamine (vitamin B1), yielding short peptide fragments associated with the vitamin. It functions as a skin-conditioning agent, intended to deliver B1 in a more skin-compatible matrix than the free vitamin. There is no specific CIR review; safety relies on the broader track record of yeast hydrolysates and B-vitamin carriers, both well tolerated at cosmetic levels. Yeast-derived materials carry a small allergen risk for highly sensitive users. Most efficacy data is supplier-generated and not independently replicated, so claims should be treated as suggestive rather than proven.

Function

SKIN CONDITIONING

Skin benefits

  • Vitamin B1 carrier with skin-compatible matrix
  • Supports skin conditioning
  • Yeast-derived biocompatibility

Known concerns

  • Sparse independent efficacy data
  • Possible allergen risk in yeast-sensitive users
  • No formal CIR/SCCS dossier

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.