Skin Conditioning
ACETYL HEPTAPEPTIDE-69
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A synthetic 7-amino-acid peptide with an acetyl cap, sold as a skin-conditioning active. Plausibly safe; independent data is limited.
Acetyl Heptapeptide-69 is a synthetic heptapeptide modified at the N-terminus with an acetyl group, used in cosmetic formulations as a skin-conditioning agent at low ppm levels. Numbered INCI peptides of this type are supplied by specialty ingredient houses for signaling-type benefits. There is no CIR or SCCS opinion for this exact peptide and no published GHS classification. Short peptides have negligible intact penetration and very low irritation potential. The main uncertainty is the absence of independent efficacy and long-term safety literature; risk in practice is dominated by the rest of the formulation rather than the peptide itself.
Function
Skin benefits
- Skin conditioning
- Improved stability via acetylation
- Low irritation potential
Known concerns
- No regulatory review
- Limited independent data
- Supplier-driven claims
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.