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Chelating Agent

TRIETHYLENETETRAMINE HCL

CAS 38260-01-4 Updated
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A polyamine (trientine HCl) primarily known as a Wilson's disease drug — not a typical cosmetic ingredient. GHS-flagged for skin, eye, and respiratory irritation; we score in the red.

Function

CHELATING

Skin benefits

  • Chelating and pH-adjusting potential
  • Industrial precedent in metal sequestration

Known concerns

  • GHS H315 skin irritation
  • GHS H319 serious eye irritation
  • GHS H335 respiratory irritation
  • Not a recognized cosmetic ingredient — used pharmaceutically (trientine) for Wilson's disease
  • Sensitization potential typical of polyamines

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.