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Fragrance

TRIMETHYL-6-THIABICYCLOOCTANE

CAS 68398-18-5
72

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A sulfur-containing synthetic fragrance note that delivers tropical and grapefruit facets at trace dosage. Effective but limited public safety data.

Trimethyl-6-thiabicyclooctane (CAS 68398-18-5) is a synthetic bicyclic sulfur-containing fragrance ingredient used in perfumery for tropical, sulfurous grapefruit-type notes. Sulfur fragrance materials are extremely potent and dosed at parts-per-million in finished products. Public toxicology data are sparse; IFRA and industry RIFM evaluations may set use-level standards. Not a known sensitizer at typical trace use. Because it is a specialty material with limited open literature, conservative scoring applies.

Function

PERFUMING

Skin benefits

  • Adds grapefruit/tropical facets
  • Used at trace levels — minimal exposure

Known concerns

  • Thin public safety dossier
  • Potential IFRA use-level restriction
  • Sulfur potency demands careful dosing

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.