Botanical Extract
TRIPTERYGIUM WILFORDII ROOT EXTRACT
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
Thunder god vine root — contains triptolide, a known multi-organ toxin (liver, kidney, reproductive). Not appropriate for cosmetic skincare. Avoid.
Function
Skin benefits
- Triptolide has potent anti-inflammatory activity (medicinal context)
Known concerns
- Contains triptolide — known hepatotoxin, nephrotoxin, gonadotoxin
- Reproductive toxicity documented in animal and human reports
- Cardiotoxic at supra-cosmetic doses
- Use restricted to controlled clinical trials per published reviews
- Inappropriate for over-the-counter cosmetic use
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related botanical extracts
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.