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Botanical Extract

SANGUINARIA CANADENSIS ROOT EXTRACT

CAS 84929-48-6 Updated
18

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Bloodroot root extract — a sanguinarine-rich botanical with documented oral leukoplakia in toothpaste use and severe skin necrosis from black-salve products. Not advisable for cosmetics.

Function

SKIN CONDITIONING

Skin benefits

  • Traditional antimicrobial use
  • Astringent action

Known concerns

  • Sanguinarine causes oral leukoplakia (premalignant)
  • Black-salve products caused severe skin necrosis
  • DNA-intercalating alkaloid
  • Avoid in cosmetic formulations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.