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Skin Conditioning

URSODIOL

CAS 128-13-2 Updated
65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Ursodiol (ursodeoxycholic acid) is a bile acid more familiar as an oral medication for liver disease, occasionally explored topically for barrier support. H315/H319 irritation flags and limited cosmetic data hold it in mid-Yellow.

Function

SKIN PROTECTINGSKIN CONDITIONING - MISCELLANEOUS

Skin benefits

  • Bile-acid skin-conditioning agent investigated for barrier and anti-inflammatory effects
  • Endogenous bile acid — natural to mammalian biology
  • Studied as a potential adjunct for cholestatic skin conditions

Known concerns

  • GHS H315 (skin irritation) and H319 (eye irritation)
  • Topical use is non-mainstream — primarily an oral medication for liver disease
  • Limited cosmetic-specific safety dossier

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related skin conditionings

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.