Skip to content

Skin Conditioning

URSODIOL

CAS 128-13-2
65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Ursodiol (ursodeoxycholic acid) is a bile acid more familiar as an oral medication for liver disease, occasionally explored topically for barrier support. H315/H319 irritation flags and limited cosmetic data hold it in mid-Yellow.

Function

SKIN PROTECTINGSKIN CONDITIONING - MISCELLANEOUS

Skin benefits

  • Bile-acid skin-conditioning agent investigated for barrier and anti-inflammatory effects
  • Endogenous bile acid — natural to mammalian biology
  • Studied as a potential adjunct for cholestatic skin conditions

Known concerns

  • GHS H315 (skin irritation) and H319 (eye irritation)
  • Topical use is non-mainstream — primarily an oral medication for liver disease
  • Limited cosmetic-specific safety dossier

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related skin conditionings

65
(ANGELICA GIGAS/CNIDIUM OFFICINALE/PAEONIA LACTIFLORA) ROOT EXTRACT
Skin Conditioning
 65
(SH-OLIGOPEPTIDE-78 S-FRUIT FLY OLIGOPEPTIDE-1) PEPTIDES
Skin Conditioning
 65
(SH-PENTAPEPTIDE-10 6-AMINOCAPROOYL SH-PENTAPEPTIDE-11) SP
Skin Conditioning
 65
ABELMOSCHUS MANIHOT CALLUS EXTRACELLULAR VESICLES
Skin Conditioning
 65
ABIES BALSAMEA EXTRACT
Skin Conditioning
 65
ACEFYLLINE METHYLSILANOL MANNURONATE
Skin Conditioning
 65
ACETAMINO METHYLSULFONYLBUTYROYL DIPEPTIDE-57
Skin Conditioning
 65
ACETOBACTER/SACCHAROMYCES/SALIX ALBA BARK/PELARGONIUM GRAVEOLENS FLOWER/(CARICA PAPAYA/CITRUS LIMON) FRUIT/(CAMELLIA SINENSIS/CARICA PAPAYA) LEAF/(CHICORY/LICORICE) ROOT/HELIANTHUS TUBEROSUS TUBER/LACTARIUS DELICIOSUS/ARMILLARIA MELLEA/CYMBOPOGON SCHOENANTHUS FERMENT FILTRATE
Skin Conditioning

Check your shelf

Find URSODIOL in your products.

Scan any cosmetic product with LuxSense to see if it contains URSODIOL and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.