Xylidines, their isomers, salts and halogenated and sulphonated derivatives

Other

2

Avoid

CAS Number: 1300-73-8

About Xylidines, their isomers, salts and halogenated and sulphonated derivatives

A group of toxic aromatic amines — suspected carcinogens banned in cosmetics. Fatal if inhaled, toxic by all routes.

Detailed Analysis

Xylidines (dimethylanilines) are aromatic amines classified H301+H311+H331 (toxic by all routes), H330 (fatal if inhaled for some isomers), H351 (suspected carcinogen), and H373 (chronic organ damage). Like other aromatic amines, they cause methemoglobinemia and are suspected bladder carcinogens. All isomers, salts, and derivatives are prohibited under EU Cosmetics Regulation Annex II.

Known Concerns

  • EU Annex II banned substance
  • Suspected carcinogen (H351)
  • Fatal if inhaled (some isomers)
  • Toxic by all routes
  • Causes methemoglobinemia
  • Chronic organ damage
  • Toxic to aquatic life

Safety Score

2

Avoid

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.