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Hair Dye

1,2,4-BENZENETRIACETATE

CAS 613-03-6
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

An acetylated trihydroxybenzene used as a hair-dye coupler. The acetyl groups reduce reactivity during formulation; use is concentration-limited.

1,2,4-Benzenetriacetate (CAS 613-03-6) is the triacetate ester of 1,2,4-trihydroxybenzene (hydroxyquinol). It is used in oxidative hair-dye systems as a coupler/modifier; the acetate groups protect the reactive triol during storage and hydrolyze during application. SCCS and cosmetic-industry reviews apply concentration limits in hair-dye use. Post-hydrolysis the polyphenol can undergo further oxidation with dye developers to form colored species. Long-term safety data is modest. Not classified CMR. Score sits at the border of Moderate/orange and yellow — reduced reactivity of the ester form helps, but parent polyphenol concerns and limited data keep it orange.

Function

HAIR DYEING

Skin benefits

  • Oxidative hair-dye coupler function
  • Acetyl protection reduces in-product reactivity
  • SCCS-evaluated concentration limits

Known concerns

  • Hydrolyzes to reactive polyphenol
  • Thin independent safety data
  • Hair-dye category concerns apply

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.