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HC YELLOW NO. 15

CAS 138377-66-9
54

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Hc Yellow No. 15 is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

HC Yellow No. 15 is a nitro-substituted m-phenylenediamine derivative that functions as a primary intermediate in oxidative hair colouring systems, contributing yellow-gold tones. The chemical structure contains both amino and nitro groups on the aromatic ring, a combination that gives high tinctorial power but also raises concern for metabolic activation to sensitising intermediates. EU SCCS assessment for this structural class typically results in concentration limits for oxidative use conditions. The compound is listed in Annex III of EU Regulation 1223/2009 with a specific maximum concentration.

Known concerns

  • Skin sensitisation potential
  • Eye irritation H319
  • Nitro-aromatic amine metabolic activation concern

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.