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1-(.beta.-Ureidoethyl)amino-4-nitrobenzene

CAS 27080-42-8
58

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

1-(.beta.-ureidoethyl)amino-4-nitrobenzene is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

This nitroaniline derivative with a ureido substituent is used at a maximum concentration of 0.5% in hair dye formulations. The urea moiety may act as a slow-release group, reducing acute toxicity while maintaining coupling activity. It is not formally restricted in EU cosmetic Annexes, though its nitro group and aromatic amine structure warrant dermatological caution.

Known concerns

  • Nitro compound sensitization potential
  • Limited toxicological data
  • Aromatic amine structural alert

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.