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2-(2-HYDROXYPROPOXY)-P-PHENYLENEDIAMINE

CAS 2839861-18-4
46

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

2-(2-Hydroxypropoxy)-P-Phenylenediamine is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

This hair dye intermediate contains a 2-hydroxypropoxy substituent (-O-CH2-CH(OH)-CH3), introducing a secondary alcohol functionality to the PPD structure. The hydroxyalkyl ether chain provides enhanced water solubility compared to simpler alkyl substitutions. Like other p-phenylenediamine derivatives used in oxidative hair coloration, it is subject to EU Cosmetics Regulation Annex III restrictions under Regulation (EC) No 1223/2009. Concentration limits and cautionary labelling (particularly skin sensitization warnings) are mandatory for finished cosmetic products containing this ingredient.

Known concerns

  • Skin sensitizer - aromatic amine class
  • EU Annex III restricted - concentration and labelling requirements
  • Secondary alcohol may contribute to irritation

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.