Other
2-(2-HYDROXYPROPOXY)-P-PHENYLENEDIAMINE
Safety score · 0–100
Moderate
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
2-(2-Hydroxypropoxy)-P-Phenylenediamine is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.
This hair dye intermediate contains a 2-hydroxypropoxy substituent (-O-CH2-CH(OH)-CH3), introducing a secondary alcohol functionality to the PPD structure. The hydroxyalkyl ether chain provides enhanced water solubility compared to simpler alkyl substitutions. Like other p-phenylenediamine derivatives used in oxidative hair coloration, it is subject to EU Cosmetics Regulation Annex III restrictions under Regulation (EC) No 1223/2009. Concentration limits and cautionary labelling (particularly skin sensitization warnings) are mandatory for finished cosmetic products containing this ingredient.
Known concerns
- Skin sensitizer - aromatic amine class
- EU Annex III restricted - concentration and labelling requirements
- Secondary alcohol may contribute to irritation
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related others
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.