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2-((2-METHYLAMINO)ETHOXY)-P-PHENYLENEDIAMINE

CAS 2839861-23-1
28

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

2-((2-Methylamino)ethoxy)-P-Phenylenediamine is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

This compound functions as a primary intermediate in oxidative hair dye systems, with the methylamino-ethoxy side chain modifying both its dyeing properties and toxicological profile. The secondary amine group introduces additional reactivity and potential for N-nitrosamine formation under certain conditions. EU Regulation 1223/2009 classifies such aromatic amine hair dye precursors under Annex III restrictions, requiring careful purity control to limit exposure to unreacted amine and potential degradation products. These substances must be adequately protected in formulations to prevent premature oxidation and consumer exposure to reactive intermediates.

Known concerns

  • Skin and respiratory sensitization
  • Secondary amine raises N-nitrosamine formation concern
  • Potential for oxidative degradation products
  • Cross-sensitization with other aromatic amine hair dyes

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.