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2-(2-PROPENYLOXY)-P-PHENYLENEDIAMINE

CAS 2839861-22-0
28

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

2-(2-Propenyloxy)-P-Phenylenediamine is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

This compound is a substituted p-phenylenediamine derivative functioning as a primary intermediate in permanent hair dye formulations. Like other phenylenediamine hair dye precursors, it can undergo oxidative coupling to form colored polymeric dyes. The allyloxy substituent introduces additional reactivity concerns. Under EU Cosmetics Regulation 1223/2009, p-phenylenediamine derivatives are generally restricted under Annex III, with specific concentration limits typically capped at 2% for oxidative hair dye use due to their potential to act as skin sensitizers and form reactive intermediates.

Known concerns

  • Skin sensitization and allergic contact dermatitis
  • Potential respiratory sensitization
  • Cross-reactivity with other phenylenediamine derivatives
  • Metabolic activation to reactive intermediates

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.