2,3-Epoxypropan-1-ol (Glycidol)

Other

2

Avoid

CAS Number: 556-52-5

About 2,3-Epoxypropan-1-ol (Glycidol)

A confirmed carcinogen, mutagen, and reproductive toxicant — banned in cosmetics. One of the most hazardous epoxides.

Detailed Analysis

Glycidol (2,3-epoxy-1-propanol) is a reactive epoxy alcohol classified H350 (may cause cancer), H341 (suspected mutagen), H360F (may damage fertility), and H331 (toxic if inhaled). IARC Group 2A probable carcinogen. It combines the reactivity of an epoxide with a primary alcohol, making it a potent genotoxic agent. Prohibited under EU Cosmetics Regulation Annex II. Also a food contaminant formed during oil refining.

Known Concerns

  • ⚠ EU Annex II banned substance
  • ⚠ Probable carcinogen (IARC 2A)
  • ⚠ Suspected mutagen (H341)
  • ⚠ Damages fertility (H360F)
  • ⚠ Toxic if inhaled
  • ⚠ Reactive epoxide
  • ⚠ Genotoxic

Safety Score

2

Avoid

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.