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Banned Substance

4,4'-Oxydianiline (p-aminophenyl ether) and its salts

CAS 101-80-4
2

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

An industrial aromatic amine intermediate — IARC 2B carcinogen and Cat 1B reproductive toxin. EU Annex II banned in cosmetics. Has no legitimate cosmetic use; classified among substances of very high concern.

Skin benefits

  • No cosmetic benefits — industrial intermediate

Known concerns

  • IARC Group 2B classified carcinogen
  • Reproductive toxicity Cat 1B
  • EU Annex II banned for cosmetic use
  • Strong skin and respiratory sensitizer

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.