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2-Nitro-9H-carbazole

CAS 14191-22-1
20

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

2-nitro-9h-carbazole is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

2-Nitro-9H-carbazole is a planar nitro-polycyclic aromatic compound with known mutagenic activity in bacterial test systems. The carbazole scaffold combined with a nitro substituent creates metabolic activation concerns via nitro-reduction to reactive intermediates. It is not listed in EU cosmetic Annexes but its toxicological profile is consistent with compounds prohibited from cosmetic use. There are no approved applications or safe-use data.

Known concerns

  • Structural alerts for mutagenicity and carcinogenicity
  • Metabolic activation via nitro-reduction
  • No approved cosmetic applications

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.