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3-Chloro-2,6-Dihydroxy-4-methyl-benzaldehyde (chloroatranol)(*)

CAS 57074-21-2
28

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A potent skin sensitizer and allergen naturally occurring in oak moss and treemoss absolutes — EU IFRA standards strictly limit its presence in cosmetic products.

Chloroatranol is one of the most significant fragrance allergens identified by the SCCS, occurring naturally in oak moss and treemoss absolute extracts. It is classified H317 (skin sensitizer) and is subject to severe restrictions in the EU: IFRA standards cap its content at 0.0005% (5 ppm) in finished cosmetic products due to its exceptionally strong sensitization potential. The SCCS has explicitly stated chloroatranol should not be used in cosmetic products at levels that could cause contact allergy in sensitized individuals.

Known concerns

  • Potent skin sensitizer (H317)
  • EU IFRA restricted to ≤5 ppm in finished cosmetic products
  • Major cause of fragrance contact allergy
  • Banned or severely restricted in multiple regions

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.