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5-[(2-hydroxyethyl)amino]-o-cresol

CAS 55302-96-0
45

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A substituted cresol with hydroxyethylamino functionality used in hair dye formulations, combining sensitization and irritancy hazards with aquatic toxicity concerns.

This hydroxyethylamino-substituted cresol derivative is used as a coupling agent in oxidative hair dye systems. The compound exhibits multiple hazard statements: H315 (skin irritation), H319 (eye irritation), H335 (respiratory irritation), and H411 (aquatic toxicity). Its aminoacetal structure provides reactivity in oxidative coupling reactions but also contributes to its irritant profile. EU Annex III listing may apply depending on specific use conditions.

Known concerns

  • Skin irritant (H315)
  • Eye irritant (H319)
  • Respiratory irritant (H335)
  • Acute aquatic toxicity (H411)
  • Potential hair dye allergen

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.