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5-AMINO-4-CHLORO-O-CRESOL HCL

CAS 110102-85-7
52

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

The hydrochloric acid salt form of 5-amino-4-chloro-o-cresol, explicitly listed in EU Annex III/208 indicating regulatory restrictions for hair dye applications in the European market.

This is the HCl salt of 5-amino-4-chloro-o-cresol, listed in EU Cosmetics Regulation Annex III/208. The salt form improves water solubility which can affect its reactivity profile in oxidative hair dye systems. Annex III listing indicates this compound is permitted for hair dye use only under specified conditions and maximum concentration limits. The hydrochloride salt may increase skin irritation potential compared to the free base form.

Skin benefits

  • Used as hair dye intermediate for controlled color development

Known concerns

  • EU Annex III/208 restriction applies (specific hair dye conditions)
  • Salt form may increase irritant potential
  • Skin sensitizer concerns common to aminophenol derivatives

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.